Evaluation of chest CT findings offers an additional approach to demonstrate the effectiveness of different COVID-19 vaccines in reducing the impact of a COVID-19 diagnosis.
According to the ARRS American Journal of Roentgenology (AJR), evaluation of chest CT findings offers an additional approach to demonstrate the effectiveness of different COVID-19 vaccines in reducing the impact of a COVID-19 diagnosis. .
"The frequency and severity of pneumonia was lower in patients fully vaccinated with mRNA and adenovirus vector vaccines who experienced infections compared to unvaccinated patients," wrote corresponding author Davide Bellini of the department of radiological sciences, oncology and pathology. anatomical in "Sapienza". University of Rome.
“Visual observation by radiological imaging of the protective effect of vaccination on lung injury in patients with recurrent infections provides additional evidence supporting the clinical benefit of vaccination,” reiterated the authors of this AJR article.
The single-center study by Bellini and colleagues included 467 patients (250 men, 217 women; median age, 65 years) who underwent chest CT between December 15, 2021 and February 18, 2022 during hospitalization for symptomatic COVID-19, confirmed by reverse transcriptase-polymerase chain reaction assay.
A total of 216 patients were unvaccinated , while 167 and 84 patients were fully vaccinated , having received a second dose at least 14 days before COVID-19 diagnosis, with the BNT162b2 mRNA vaccine or the adenovirus vector vaccine ChAdOx1-S, respectively.
The frequency of freedom from pneumonia was 15% in unvaccinated patients, compared to 51% and 29% in patients fully vaccinated with the BNT162b2 and ChAdOx1-S vaccines, respectively.
Furthermore, the mean CT-SS was significantly higher in unvaccinated patients (9.7) than in patients fully vaccinated with BNT162b2 (5.2) or ChAdOx1-S (6.2) vaccines (both p < 0.001). .
“Visual observation by radiological imaging of the protective effect of vaccination on lung injury in patients with recurrent infections provides additional evidence supporting the clinical benefit of vaccination,” reiterated the authors of this AJR article.
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