Overdiagnosis of Melanocytic Skin Lesions Raises Concerns

Many pathologists acknowledge the phenomenon of overdiagnosis in skin cancer, highlighting the need for standardized diagnostic criteria and continued education to minimize unnecessary treatments and psychological distress in patients.

December 2022
Overdiagnosis of Melanocytic Skin Lesions Raises Concerns

Overdiagnosis of Melanocytic Skin Lesions Raises C

Summary

Background :

Post-surgical skin healing can lead to different types of scars, ranging from a fine line to pathological scars, in relation to the patient’s intrinsic and extrinsic factors.

Although the role of nutrition in influencing skin healing is known, no previous studies investigated whether a vegan diet can affect post-surgical wounds.

Aim:

The objective of this study was to compare surgical scars between omnivorous and vegan patients.

Methods and materials:

This is a prospective observational study .

Twenty-one omnivorous and 21 vegan patients who underwent surgical excision of non-melanoma skin cancer were enrolled.

Postoperative complications and scar quality were evaluated using the modified Scar Cosmesis Assessment and Rating (SCAR) scale.

Results:

Vegans showed significantly lower mean serum iron (p < .001) and vitamin B12 (p < .001). Wound diastasis was more common in vegans (p = 0.008).

After 6 months, vegan patients had a higher modified SCAR score than omnivores (p < .001), showing the worst scar extent (p < .001), more frequent atrophic scars (p < .001), and worse general impression (p <.001) <0.001).

Conclusion:

This study suggests that a vegan diet may negatively influence the outcome of surgical scars.