Sexual Dimorphism in COVID-19: Gender Disparities in Disease Severity and Outcomes
COVID-19 severity and mortality are higher in men compared to women, while women may be at higher risk of reinfection and long COVID, highlighting gender-specific disparities in COVID-19 susceptibility, clinical course, and outcomes.
October 2022
Early Remdesivir Use to Prevent Severe COVID-19: Clinical Trial Outcomes
Early remdesivir administration results in an 87% lower risk of hospitalization or death compared to placebo in individuals with COVID-19, highlighting the therapeutic potential of remdesivir in preventing disease progression and reducing the burden of severe illness in infected patients.
October 2022
Herd Immunity Unlikely for COVID-19: Public Health Implications
Achieving herd immunity against COVID-19 is unlikely, necessitating continued vaccination efforts, treatment development, and ensuring adequate healthcare capacity to mitigate the impact of the ongoing pandemic and prevent future surges in infections.
October 2022
Clinical Evolution One Year After ICU Admission for COVID-19: Long-Term Sequelae
Weakness, musculoskeletal, and work-related problems persist as long-term sequelae of critical illness episode one year after ICU admission for COVID-19, highlighting the need for comprehensive rehabilitation and support services to address post-intensive care syndrome and improve long-term functional outcomes in survivors.
October 2022
Frequency of Adverse Events in Placebo Arms of COVID-19 Vaccine Trials: Clinical Insights
A significant proportion of adverse events reported in placebo arms of COVID-19 vaccine trials are attributable to the placebo effect, highlighting the importance of placebo-controlled trials in assessing vaccine safety and efficacy.
October 2022
Chronic Bilateral Dacryoadenitis Associated with COVID-19: Ocular Manifestations
SARS-CoV-2 infection can affect tear gland tissue, leading to chronic bilateral dacryoadenitis, highlighting the diverse ophthalmic manifestations of COVID-19 and underscoring the importance of comprehensive ocular evaluation in patients with systemic viral illnesses.
October 2022
Multi-Organ Evaluation After SARS-CoV-2 Infection: Long-Term Sequelae
Subjects who apparently recovered from SARS-CoV-2 infection exhibit signs of subclinical multi-organ involvement, highlighting the need for comprehensive long-term follow-up and surveillance to monitor for potential late effects and complications of COVID-19.
October 2022
Non-Invasive Respiratory Strategies in Acute ARDS due to COVID-19: Clinical Outcomes
An initial continuous positive airway pressure (CPAP) strategy significantly reduces the risk of tracheal intubation or mortality in patients with acute ARDS due to COVID-19, underscoring the importance of early non-invasive respiratory support in improving clinical outcomes in severe COVID-19 pneumonia.
October 2022
Metabolically Unhealthy Individuals at Increased Risk for Critical COVID-19: Epidemiological Findings
Metabolic health status is more important than obesity alone in determining COVID-19 outcomes, with metabolically unhealthy individuals at increased risk for severe disease and critical illness, highlighting the importance of addressing metabolic risk factors to reduce the burden of COVID-19.
October 2022
